Clapton ranked second in Rolling Stone’s list of the “100 Greatest Guitarists of All Time” and fourth in Gibson’s “Top 50 Guitarists of All Time”. He was also named number five in Time magazine’s list of “The 10 Best Electric Guitar Players” in 2009.

In the mid-1960s Clapton left the Yardbirds to play with John Mayall & the Bluesbreakers. Immediately after leaving Mayall, Clapton formed the power trio Cream with drummer Ginger Baker and bassist Jack Bruce, in which Clapton played sustained blues improvisations and “arty, blues-based psychedelic pop”. After Cream broke up, he formed blues rock band Blind Faith with Baker, Steve Winwood, and Ric Grech.

Clapton’s solo career began in the 1970s, where his work bore the influence of the mellow style of J. J. Cale and the reggae of Bob Marley. His version of Marley’s “I Shot the Sheriff” helped reggae reach a mass market. Two of his most popular recordings were “Layla”, recorded with Derek and the Dominos; and Robert Johnson’s “Crossroads”, recorded with Cream. Following the death of his son Conor in 1991, Clapton’s grief was expressed in the song “Tears in Heaven”, which appeared on his Unplugged album.